abstract：OBJECTIVE:Recent studies have showed that genetic factors involved in the host responses might determine the severity of periodontitis. hCAP-18/LL-37 is a part of the innate immune response in the oral cavity. The aim of the present study was to investigate the mutation of CAMP gene encoding hCAP-18/LL-37 in the patien...

journal_title：Archives of oral biology

authors： Türkoğlu O,Berdeli A,Emingil G,Atilla G

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:The aim of the present study is to investigate the involvement of immunocompetent cells, pro-inflammatory cytokines and HSP, to evaluate a change of periodontal ligament during the initial stage of orthodontic tooth movement. DESIGN:In the present study, we investigated the distributional density of immunoco...

journal_title：Archives of oral biology

authors： Baba S,Kuroda N,Arai C,Nakamura Y,Sato T

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:The present study was designed to examine how oestrogen regulates proliferation, osteoblastic differentiation, collagen synthesis and periostin gene expression in primary human periodontal ligament (hPDL) cells. DESIGN:The short interfering RNA (siRNA) technique was used to inhibit oestrogen receptor beta (E...

journal_title：Archives of oral biology

authors： Mamalis A,Markopoulou C,Lagou A,Vrotsos I

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:The molecular variation of paired domain box gene 9 (PAX9) was previously investigated by our research group and a high degree of evolutionary conservation in coding and non-coding regions was observed except in exon 3. PAX9 is a transcription factor important in tooth development, and we wanted to verify its...

journal_title：Archives of oral biology

authors： Paixão-Côrtes VR,Braga T,Salzano FM,Mundstock K,Mundstock CA,Bortolini MC

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:Streptococcus mutans is known to be a primary causative agent of dental caries and its surface proteins have been investigated to specify their association with its virulence. Amongst those, 4 glucan-binding proteins (Gbps) are considered to be important factors due to their glucan-binding properties, of whic...

journal_title：Archives of oral biology

authors： Fujita K,Takashima Y,Inagaki S,Nagayama K,Nomura R,Ardin AC,Grönroos L,Alaluusua S,Ooshima T,Matsumoto-Nakano M

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Interleukin-6 (IL-6) is a potent stimulator of osteoclastic bone resorption. Osteoblast secretion of IL-6 plays an important role in the regulation of bone metabolism. Angiotensin II (Ang II) has been shown to regulate the expression of potent inflammatory factors, including MCP-1 and IL-6, by stimulating en...

journal_title：Archives of oral biology

authors： Guo L,Wang M,Zhang ZY,Hao L,Lou BY,Li XY,Loo WT,Jin L,Cheung MN

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:Interleukin-1 (IL-1) is a proinflammatory cytokine that is highly elevated in response to bacterial biofilms and is a potential risk factor for periodontal diseases. IL-1 gene polymorphisms have been associated with the IL-1 level. The aim of this study was to investigate if IL-1 gene cluster polymorphisms ar...

journal_title：Archives of oral biology

authors： Karasneh JA,Ababneh KT,Taha AH,Al-Abbadi MS,Ollier WE

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:The literature suggests that females have less adverse effects to infection than males, due to the protective effects of oestrogen. The purpose of our study is to compare the systemic effects of induced periapical lesions between groups of animals with various serum concentrations of oestrogen. METHODS:To in...

journal_title：Archives of oral biology

authors： Zhang H,Bain JL,Caskey CP,Sandifer LC,Johnson RB

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Interferon gamma (IFN-γ) is one of the key regulatory cytokines that has a significant effect on immune responses. It may be important in the chronic inflammatory diseases such as periodontitis in which increased IFN-γ levels were found. The aim of this study was to analyze +874A/T polymorphism in the IFN-γ ...

journal_title：Archives of oral biology

authors： Holla LI,Hrdlickova B,Linhartova P,Fassmann A

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVES:brain-derived neurotrophic factor (BDNF), which is produced in rat submandibular gland, is one of the most abundant neurotrophins in the central nervous system. It is generally accepted that occlusal disharmony causes stress. The purpose of the present study was to investigate whether occlusal disharmony-ind...

journal_title：Archives of oral biology

authors： Irie K,Ekuni D,Tomofuji T,Azuma T,Endo Y,Kasuyama K,Morita M

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that experimental occlusal interferences increase the nerve growth factor (NGF) levels in periodontal tissues and cause an up-regulation of preprotachykinin-A (PPTA) mRNA. BACKGROUND:NGF is related to hyperalgesia and inflammation. PPTA mRNA, a primer of substance P, is a possible fact...

journal_title：Archives of oral biology

authors： Dong Y,Wang XM,Liu HC,Widmalm SE

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of experimentally created disordered occlusion on the mandibular condylar cartilage in terms of histological morphology and expression of MMP-3, MMP-9, TIMP-1 and aggrecan. MATERIALS AND METHODS:Eighty 8-week-old Sprague-Dawley rats were randomly divided into two experimental (Exp)...

journal_title：Archives of oral biology

authors： Wang GW,Wang MQ,Wang XJ,Yu SB,Liu XD,Jiao K

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the pulpal changes associated with autogenous single-rooted immature tooth transplantation in dogs, using either one, or two-stage surgical techniques. METHODS:Teeth from 3 beagle dogs, 5 months old, were extracted and transplanted to mechanically prepared recipient ...

journal_title：Archives of oral biology

authors： Ferreira MM,Botelho MF,Abrantes M,Oliveiros B,Carrilho EV

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE AND DESIGN:Autopsies of the submandibular gland, the vestibular folds and the soft palate from 65-87 old humans were examined to record the immunohistochemical expression of MUC1 and the simple mucin-type antigens Tn and Sialyl-Tn. RESULTS:(1) The serous acini in the submucosal glands from the larynx and the...

journal_title：Archives of oral biology

authors： Kirkeby S,Moe D,Bardow A

更新日期：2010-11-01 00:00:00

abstract：:In this present study we have tested the impact of porfimer sodium (Photofrin, AXCAN PHARMA Inc., Quebec, Canada) photoactivated disinfection (PD) on cells of Streptococcus intermedius in suspension. In order to provide basic data to support future clinical studies of PD in dentistry the study used exposure to Quartz-...

journal_title：Archives of oral biology

authors： Bonstein T,Mikulski LM,Bush MA,Bush PJ

更新日期：2010-10-01 00:00:00

abstract：AIM:To compare the craniocervical angles and distances between temporomandibular dysfunction (TMD) and free TMD subjects. CASUISTIC AND METHODS:The sample consisted of young adults, of both genders, with age ranging between 18 and 30 years. TMD diagnosis was based on the clinical criteria of the Research Diagnostic Cr...

journal_title：Archives of oral biology

authors： de Farias Neto JP,de Santana JM,de Santana-Filho VJ,Quintans-Junior LJ,de Lima Ferreira AP,Bonjardim LR

更新日期：2010-09-01 00:00:00

abstract：:We report a specimen of an insular black rat (Rattus rattus) from Illa den Colom (Menorca, Western Mediterranean) displaying a singular dental characteristic. It has no molar teeth but displays regular incisors. Its mere occurrence as a regular adult rat is puzzling and we attempted to evaluate what diet and morpholog...

journal_title：Archives of oral biology

authors： Bover P,Alcover JA,Michaux J,Renaud S

更新日期：2010-08-01 00:00:00

abstract：AIM:Different enzyme-containing toothpastes are available on the market. The aim of the present in situ study was to investigate their efficacy for immobilisation of protective enzymes in the pellicle layer. METHODS:Pellicle formation took place in situ on bovine enamel slabs fixed to individual upper jaw splints carr...

journal_title：Archives of oral biology

authors： Hannig C,Spitzmüller B,Lux HC,Altenburger M,Al-Ahmad A,Hannig M

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:The radical anion of oxygen (O(-)) is extremely oxidative and shows high reactivity. In this study, the antibacterial activity of water super-oxidised water containing high concentration of O(-) (O(-)-water) was tested against cultured planktonic cells of cariogenic bacteria, periodontopathic bacteria and Can...

journal_title：Archives of oral biology

authors： Yamada K,Yama M,Takaku Y,Kakizawa T,Kimizuka R,Okuda K,Kato T

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:Interspecies interactions of oral streptococci involve the production and excretion of antimicrobial compounds to compete successfully during colonization. Bacteriocin production by Streptococcus mutans and hydrogen peroxide (H2O2) production by Streptococcus sanguinis have been demonstrated as crucial for th...

journal_title：Archives of oral biology

authors： Zhu L,Kreth J

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVES:The influence of carotid artery occlusion (10, 30 and 60 min) on regulatory mechanisms implicated in the vasorelaxant responses of isolated glandular branch of rabbit facial artery to acetylcholine (ACh) and vasoactive intestinal polypeptide (VIP) was examined. DESIGN:In organ bath studies with arterial rin...

journal_title：Archives of oral biology

authors： Roganović J,Radenković M,Stojić D

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:Wnt5a is generally considered a non-canonical Wnt family member and plays an important role in the development of several tissues through regulation of cell fate, proliferation, migration, polarity and death. This study investigates its expression mode in human tooth development and the involved cell signal t...

journal_title：Archives of oral biology

authors： Peng L,Dong G,Xu P,Ren LB,Wang CL,Aragon M,Zhou XD,Ye L

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:The existence of stem/progenitor cells in dental tissue has been suggested but their characterization in the human tooth germ remains elusive. The purpose of this study was to investigate these cells in human dental follicles and dental papillae at the crown-forming stage and compare their potential for hard ...

journal_title：Archives of oral biology

authors： Yagyuu T,Ikeda E,Ohgushi H,Tadokoro M,Hirose M,Maeda M,Inagake K,Kirita T

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:Streptococcus mutans, known to be a major pathogen of dental caries, is also considered to cause infective endocarditis. Its 120-kDa Cnm protein binds to type I collagen, which may be a potential virulence factor. In this study, we characterized S. mutans clinical strains focusing on the cnm gene encoding Cnm...

journal_title：Archives of oral biology

authors： Nakano K,Nomura R,Taniguchi N,Lapirattanakul J,Kojima A,Naka S,Senawongse P,Srisatjaluk R,Grönroos L,Alaluusua S,Matsumoto M,Ooshima T

更新日期：2010-01-01 00:00:00

abstract：AIM:This study was planned to investigate whether smoker patients with inflammatory periodontal disease exhibit different salivary concentrations of C-telopeptide pyridinoline cross-links of type I collagen (ICTP) and osteocalcin (OC) compared to the non-smoker and/or ex-smoker counterparts. METHODS:Whole saliva sampl...

journal_title：Archives of oral biology

authors： Gürlek O,Lappin DF,Buduneli N

更新日期：2009-12-01 00:00:00

abstract：AIMS:Anomalies of tooth number may not be isolated conditions but may have wider associations in the development of the dentition including tooth size. This study aimed to examine links between hypodontia, supernumerary teeth and crown size, considering the effect on the development of the whole dentition and so increa...

journal_title：Archives of oral biology

authors： Brook AH,Griffin RC,Smith RN,Townsend GC,Kaur G,Davis GR,Fearne J

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:Calpain is a calcium ion-dependent cysteine protease, consisting of two primary isoforms (calpain1/calpain2) which mediate crucial cellular functions. The activity of the calpains is tightly regulated by the endogenous inhibitor calpastatin. Calpains have been detected in several studies during the embryonic ...

journal_title：Archives of oral biology

authors： Matsunaga T,Yamamoto G,Tachikawa T

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:Primary pulp cell cultures are frequently used to study cellular responses, odontogenic potential and stem cell responses. Their isolation and expansion via a range of technical approaches are widely reported. The purpose of this study was to investigate the influence of isolation approach and extended expans...

journal_title：Archives of oral biology

authors： Patel M,Smith AJ,Sloan AJ,Smith G,Cooper PR

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:This in vitro study was undertaken to assess the effects of Galla chinensis extract on inhibition of enamel caries-like demineralization and to elucidate the role of the organic matrix of enamel in this process. DESIGN:Either regular or enamel disposed of its organic matrix both of bovine origin were exposed...

journal_title：Archives of oral biology

authors： Zhang L,Xue J,Li J,Zou L,Hao Y,Zhou X,Li W

更新日期：2009-09-01 00:00:00

abstract：:It is well known that low-molecular weight hyaluronan (HA) is detected in human periodontal tissue under inflammatory conditions. HA oligosaccharide (HAoligo) has been demonstrated to induce matrix metalloproteinase (MMP)-1 expression in dendritic cells and chondrocytes, however, the bioactivities of HAoligo in period...

journal_title：Archives of oral biology

authors： Nakatani Y,Tanimoto K,Tanaka N,Tanne Y,Kamiya T,Kunimatsu R,Tanaka E,Tanne K

更新日期：2009-08-01 00:00:00

abstract：:The aim of this study was to investigate the potential effects of vitamin K1 supplementation on skeletal changes related to fluoride in growing rats. Forty male Wistar rats aged 4 weeks were assigned at random into three groups: high-dose fluoride (125 ppm) group; high-dose fluoride + vitamin K1 (0.2 mg/(g day)) group...

journal_title：Archives of oral biology

authors： Cadir B,Kürkcü M,Oz ĺA,Benlidayi ME

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:The inflammatory cytokine interleukin-1 (IL-1) decreases mineralisation by immortalized mouse-derived cementoblastic cells (OC-CM cells), whilst various prostanoids, including fluprostenol (flup) increase it. Subtraction hybridisation conducted on flup minus IL-1-treated OC-CM cells revealed that one of the p...

journal_title：Archives of oral biology

authors： Moldovan SM,Nervina JM,Tetradis S,Camargo PM

更新日期：2009-05-01 00:00:00

abstract：:In the complex neurovascular control of the orofacial area, the only vasoconstrictor action is mediated by the sympathetic nervous system; however, its functional role is still unclear as little evidence exists of vasoconstrictor responses to physiological stimuli in both animal and human models. Aim of the present st...

journal_title：Archives of oral biology

authors： Roatta S,Mohammed M,Passatore M

更新日期：2009-04-01 00:00:00

abstract：:Small GTPase Rab27 has been implicated in the regulation of different types of membrane trafficking, including melanosome transport and various regulated secretion events. We have previously shown that Rab27 and its effectors, Slac2-c/MyRIP and Slp4-a/granuphilin-a, are involved in the control of isoproterenol (IPR)-i...

journal_title：Archives of oral biology

authors： Imai A,Fukuda M,Yoshie S,Nashida T,Shimomura H

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:Recent developments in molecular biological techniques have increased understanding of the distribution of oral bacterial species in clinical specimens, though few investigations have been conducted to simultaneously detect oral streptococcal and periodontal species in the same specimens. The purpose of the p...

journal_title：Archives of oral biology

authors： Miyamoto E,Nakano K,Fujita K,Nomura R,Okawa R,Matsumoto M,Ooshima T

更新日期：2009-04-01 00:00:00

abstract：:Nicotine, a major component in tobacco smoke, stimulates the synthesis of prostaglandin E(2). We investigated the involvement of the transcription nuclear factor kappa B (NFkappaB) in the nicotine-induced expression of cyclooxygenase-2 (COX-2), a key enzyme for prostaglandin synthesis, in human gingival fibroblasts. N...

journal_title：Archives of oral biology

authors： Nakao S,Ogata Y,Sugiya H

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:To determine whether chewing side preference is related to handedness and lateral asymmetry of occlusal characteristics, muscular force and temporomandibular disorders (TMD) in a dentate population. DESIGN:One hundred and seventeen dentate adults participated in this cross-sectional study. Static and dynamic...

journal_title：Archives of oral biology

authors： Martinez-Gomis J,Lujan-Climent M,Palau S,Bizar J,Salsench J,Peraire M

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:This study reports the expression of proinflammatory cytokines in temporomandibular joint (TMJ) of patients affected with temporomandibular osteoarthritis (OA). DESIGN:In twelve OA of the TMJ (OA-TMJ) affected patients and in six healthy volunteer subjects studied as control, the expression of IL1beta (inter...

journal_title：Archives of oral biology

authors： Vernal R,Velásquez E,Gamonal J,Garcia-Sanz JA,Silva A,Sanz M

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:To investigate the association between passive smoking, as determined by salivary cotinine level, and caries, salivary pH, buffering capacity, flow rate and microbiological counts in young children. DESIGN:Ninety passive smokers (PS) with a mean age of 5.02 years and 90 healthy age-matched controls were incl...

journal_title：Archives of oral biology

authors： Avşar A,Darka O,Topaloğlu B,Bek Y

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:The neonatal line (NNL) is in principle found in all primary teeth and the line represents the time of birth. Earlier findings of the appearance of the NNL in light microscope and in microradiographs have shown not only changes in the prism direction of the enamel, but that the NNL has a hypomineralized chara...

journal_title：Archives of oral biology

authors： Sabel N,Johansson C,Kühnisch J,Robertson A,Steiniger F,Norén JG,Klingberg G,Nietzsche S

更新日期：2008-10-01 00:00:00